terça-feira, 9 de dezembro de 2014

Using Old Solutions to New Problems - Natural Drug Discovery in the 21st Century

Edited by Marianna Kulka, ISBN 978-953-51-1158-0, 424 pages, Publisher: InTech, Chapters published June 19, 2013 under CC BY 3.0 license
DOI: 10.5772/46069

The medicinal use of plants, animals and microorganisms has been a part of human evolution and likely began before recorded history. Is it possible that this knowledge can be used to create powerful new drugs and solve some of the human health problems facing us today? This book is a collection of an expert team of agronomists, chemists, biologists and policy makers who discuss some of the processes involved in developing a naturally-sourced bioactive compound into a drug therapy. These experts define a natural compound and elucidate the processes required to find, extract and define a naturally-derived bioactive molecule. Finally, they describe the necessity for understanding the fundamental mechanisms of disease before applying bioactive molecules in bioassay-guided drug discovery platforms.

Chapter 1 Discovery, Development, and Regulation of Natural Productsby Juergen Krause and Gailene Tobin
Chapter 3 Magnetic Resonance Technologies: Molecules to Medicineby Nadine Merkley, Ian Burton, Tobias Karakach and Raymond T. Syvitski
Chapter 4 Marine Natural Products for Protein Misfolding Modulationby James C. Giffin and Kathryn Vanya Ewart
Chapter 6 Anticancer Properties of Phytochemicals Present in Medicinal Plants of North Americaby Wasundara Fernando and H. P. Vasantha Rupasinghe
Chapter 7 A New Perspective on the Development of Cholesterol- Lowering Productsby Sandhya V.G. Nair and Yanwen Wang
Chapter 10 Asthma in the 21st Century — Unexpected Applications of Ancient Treatmentsby Priyanka Pundir, Xiaofeng Wang and Marianna Kulka

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