Edited by Oluwafemi Oguntibeju, ISBN 978-953-51-1215-0, 369 pages, Publisher: InTech, Chapters published February 05, 2014 under CC BY 3.0 license
DOI: 10.5772/57029
The human system employs the use of endogenous enzymatic as well as non-enzymatic antioxidant defence systems against the onslaught of free radicals and oxidative stress. Enzymatic antioxidants and non-enzymatic antioxidants work synergistically with each other, using different mechanisms against different free radicals and stages of oxidative stress. Dietary and lifestyle modifications are seen as the mainstay of treatment and management of chronic diseases such as diabetes mellitus. The major aims of dietary and lifestyle changes are to reduce weight, improve glycaemic control and reduce the risk of coronary heart disease, which accounts for 70- 80% of deaths among those with diabetes. It is also important to note that medicinal plants have been used as medicines since ancient time, and continue to play significant role even in modern medicine in management and treatment of chronic diseases. Impressive numbers of modern therapeutic agents have been developed from plants. Phytochemicals have been isolated and characterised from fruits such as grapes and apples, vegetables such as broccoli and onion, spices such as turmeric, beverages such as green tea and red wine, as well as many other sources. The WHO estimates that approximately 80% of the worlds inhabitants rely on traditional medicine for their primary health care and many medicinal plants have ethno-medical claims of usefulness in the treatment of diabetes and other chronic diseases globally, and have been employed empirically in antidiabetic, antihyperlipidemic, antihypertensive, antinflammatory and antiparasitic remedies. This book examines the role of antioxidant-rich natural products in management and treatment of diabetes and other chronic diseases.
Chapter 1 Lipid Profile, Antidiabetic and Antioxidant Activity of Acacia ataxacantha Bark Extract in Streptozotocin-Induced Diabetic Ratsby Rotimi O. Arise, Aderounmu I. Ganiyu and Oluwafemi O. Oguntibeju
Chapter 2 Oxidative Stress and Diabetic Complications: The Role of Antioxidant Vitamins and Flavonoidsby Omolola R. Ayepola, Nicole L. Brooks and Oluwafemi O. Oguntibeju
Chapter 3 Anti-Diabetic Effects of Nigerian Indigenous Plant Foods/Dietsby Elizabeth A. Udenta, Ikemefuna C. Obizoba and Oluwafemi O. Oguntibeju
Chapter 4 Some Selected Medicinal Plants with Antidiabetic Potentialsby A.A. Oyagbemi, M. Salihu, O.O. Oguntibeju, A.J. Esterhuyse and E.O. Farombi
Chapter 5 The Antidiabetic Activities of the Aqueous Leaf Extract of Phyllanthus Amarus in some Laboratory Animalsby Adeolu Adedapo, Sunday Ofuegbe and Oluwafemi Oguntibeju
Chapter 6 Antidiabetic Botanicals and their Potential Benefits in the Management of Diabetes Mellitusby Afolabi Clement Akinmoladun, Ebenezer Olatunde Farombi and Oluwafemi Omoniyi Oguntibeju
Chapter 7 Antioxidant-Rich Natural Grain Products and Human Healthby Afam I.O. Jideani, Henry Silungwe, Thakhani Takalani, Tonna A. Anyasi, Henry Udeh and Adewale Omolola
Chapter 8 Nutritional, Therapeutic, and Prophylactic Properties of Vigna subterranea and Moringa oleiferaby Victoria Adaora Jideani and Claudine Florett Diedericks
Chapter 9 Dietary Antioxidant Properties of Vegetable Oils and Nuts – The Race Against Cardiovascular Disease Progressionby Wongama Given Pantsi, Dirk Jacobus Bester, Adriaan Johannes Esterhuyse and Guillaume Aboua
Chapter 10 Plants with Hypolipidaemic Effects from Nigerian Floraby Ngozi Justina Nwodo, Charles Okeke Nnadi, Akachukwu Ibezim and Chika John Mbah
Chapter 11 Garlic and Its Effects on Health with Special Reference to the Reproductive Systemby Carlo Valente, Guillaume Aboua and Stefan S. Du Plessis
Chapter 12 Potentials of Phytotherapeutic Treatment of Erectile Dysfunctionby Guillaume Aboua, Claudine Manirafasha, Boitumelo R. Mosito, Michelle van der Linde and Stefan S. du Plessis
Chapter 13 Buchu – The Multi-Purpose Ethnomedicinally Important Specie and Its Benefits in the Reproductive Systemby Bongekile Skosana, Guillaume Aboua and Stefan S du Plessis
Chapter 14 Antioxidant -Rich Natural Products and Diabetes Mellitusby Ayodeji B. Oyenihi, Nicole L. Brooks, Oluwafemi O. Oguntibeju and Guillaume Aboua
Chapter 15 Potential Role of Parkia biglobosa in the Management and Treatment of Cardiovascular Diseasesby O.B.L. Alinde, A.J. Esterhuyse and O.O. Oguntibeju
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