Tobacco-smoking moms and dads increase diabetes risk for children in utero

Date: February 10, 2015

Source: University of California - Davis

Summary:

Children exposed to tobacco smoke from their parents while in the womb are predisposed to developing diabetes as adults.

Children exposed to tobacco smoke from their parents while in the womb are predisposed to developing diabetes as adults, according to a study from the University of California, Davis and the Berkeley nonprofit Public Health Institute.

In the study, published Feb. 9 in the Journal of Developmental Origins of Health and Disease, women whose mothers smoked while pregnant were two to three times as likely to be diabetic as adults. Dads who smoked while their daughter was in utero also contributed to an increased diabetes risk for their child, but more research is needed to establish the extent of that risk.

"Our findings are consistent with the idea that gestational environmental chemical exposures can contribute to the development of health and disease," said lead author Michele La Merrill, an assistant professor of environmental toxicology at UC Davis.

The study analyzed data from 1,800 daughters of women who had participated in the Child Health and Development Studies, an ongoing project of the Public Health Institute. The CHDS recruited women who sought obstetric care through Kaiser Permanente Foundation Health Plan in the San Francisco Bay Area between 1959 and 1967. The data was originally collected by PHI to study early risk of breast cancer, which is why sons were not considered in this current study.

In previous studies, fetal exposure to cigarette smoke has also been linked to higher rates of obesity and low birth weight. This study found that birth weight did not effect whether the daughters of smoking parents developed diabetes.

"We found that smoking of parents is by itself a risk factor for diabetes, independent of obesity or birth weight," said La Merrill. "If a parent smokes, you're not protected from diabetes just because you're lean."

Story Source:

The above story is based on materials provided by University of California - Davis.Note: Materials may be edited for content and length.

Journal Reference:

M. A. La Merrill, P. M. Cirillo, N. Y. Krigbaum, B. A. Cohn. The impact of prenatal parental tobacco smoking on risk of diabetes mellitus in middle-aged women. Journal of Developmental Origins of Health and Disease, 2015; 1 DOI: 10.1017/S2040174415000045

Cite This Page:

University of California - Davis. "Tobacco-smoking moms and dads increase diabetes risk for children in utero." ScienceDaily. ScienceDaily, 10 February 2015. <www.sciencedaily.com/releases/2015/02/150210050951.htm>.