Edited by Ayman Noreddin, ISBN 978-953-51-0533-6, 388 pages, Publisher: InTech, Chapters published April 20, 2012 under CC BY 3.0 license
DOI: 10.5772/1982
This book, "Readings in Advanced Pharmacokinetics - Theory, Methods and Applications", covers up to date information and practical topics related to the study of drug pharmacokinetics in humans and in animals. The book is designed to offer scientists, clinicians and researchers a choice to logically build their knowledge in pharmacokinetics from basic concepts to advanced applications. This book is organized into two sections. The first section discusses advanced theories that include a wide range of topics; from bioequivalence studies, pharmacogenomics in relation to pharmacokinetics, computer based simulation concepts to drug interactions of herbal medicines and veterinary pharmacokinetics. The second section advances theory to practice offering several examples of methods and applications in advanced pharmacokinetics.
Chapter 1 
Bioequivalence Studies by Aisha Qayyum
Bioequivalence Studies by Aisha Qayyum
Chapter 2 Computer Simulations as a Tool for Optimizing Bioequivalence Trials by Carmen Navarro-Fontestad,Victor Mangas-Sanjuán, Isabel González-Álvarez, Alfredo García-Arieta, Carlos Fernández-Teruel, Vicente G. Casabó-Alós and Marival Bermejo
Computer Simulations as a Tool for Optimizing Bioequivalence Trials by Carmen Navarro-Fontestad,Victor Mangas-Sanjuán, Isabel González-Álvarez, Alfredo García-Arieta, Carlos Fernández-Teruel, Vicente G. Casabó-Alós and Marival Bermejo
Chapter 3 Evaluation of Percutaneous Drug Permeation Using a Lateral Sectioning Approach by Nobuhiro Goi, Katsunori Morishita, Akihito Taniguchi and Takayuki Ishii
Evaluation of Percutaneous Drug Permeation Using a Lateral Sectioning Approach by Nobuhiro Goi, Katsunori Morishita, Akihito Taniguchi and Takayuki Ishii
Chapter 4 Pharmacogenomics Dictate Pharmacokinetics: Polymorphisms in Drug-Metabolizing Enzymes and Drug-Transporters by Debasis Mondal, Samantha L. Gerlach, Amrita Datta, Geetika Chakravarty and Asim B. Abdel-Mageed
Pharmacogenomics Dictate Pharmacokinetics: Polymorphisms in Drug-Metabolizing Enzymes and Drug-Transporters by Debasis Mondal, Samantha L. Gerlach, Amrita Datta, Geetika Chakravarty and Asim B. Abdel-Mageed
Chapter 5 Genetic Variation in Drug Disposition by Balmukunda Regmi and Laxman Bharati
Genetic Variation in Drug Disposition by Balmukunda Regmi and Laxman Bharati
Chapter 6 Application of Pharmacokinetics/Pharmacodynamics (PK/PD) in Designing Effective Antibiotic Treatment Regimensby Ghada F. Ahmed and Ayman M. Noreddin
Application of Pharmacokinetics/Pharmacodynamics (PK/PD) in Designing Effective Antibiotic Treatment Regimensby Ghada F. Ahmed and Ayman M. Noreddin
Chapter 7 Pharmacokinetics and Drug Interactions of Herbal Medicines: A Missing Critical Step in the Phytomedicine/Drug Development Processby Obiageri O. Obodozie
Pharmacokinetics and Drug Interactions of Herbal Medicines: A Missing Critical Step in the Phytomedicine/Drug Development Processby Obiageri O. Obodozie
Chapter 8 Pharmacokinetics of Antimicrobials in Food Producing Animalsby S. K. Bhavsar and A. M. Thaker
Pharmacokinetics of Antimicrobials in Food Producing Animalsby S. K. Bhavsar and A. M. Thaker
Chapter 9 Comparative Veterinary Pharmacokineticsby Akos Jerzsele
Comparative Veterinary Pharmacokineticsby Akos Jerzsele
Chapter 10 Observer-Based Strategies for Anesthesia Drug Concentration Estimation by Jin-Oh Hahn, Guy A. Dumont and J. Mark Ansermino
Observer-Based Strategies for Anesthesia Drug Concentration Estimation by Jin-Oh Hahn, Guy A. Dumont and J. Mark Ansermino
Chapter 11 Optimal Pharmacokinetics of Cyclosporine and Tacrolimus Based Relationship Among AUC, Trough and Peak Concentration by Hironori Takeuchi
Optimal Pharmacokinetics of Cyclosporine and Tacrolimus Based Relationship Among AUC, Trough and Peak Concentration by Hironori Takeuchi
Chapter 12 Pharmacokinetics and Metabolized Caroteniods in Liver of Single Dose Administration in Fancy Carp (Cyprinus carpio) by Bundit Yuangsoi
Pharmacokinetics and Metabolized Caroteniods in Liver of Single Dose Administration in Fancy Carp (Cyprinus carpio) by Bundit Yuangsoi
Chapter 13 Correlation of in vitro Dissolution Profiles with in vivo Pharmacokinetic Parameters of Some Commercial Brands of Aspirin Tablets Marketed in Nigeria by Emmanuel Adelaja Bamigbola
Correlation of in vitro Dissolution Profiles with in vivo Pharmacokinetic Parameters of Some Commercial Brands of Aspirin Tablets Marketed in Nigeria by Emmanuel Adelaja Bamigbola
Chapter 14 Bioavailability of Citrus Polymethoxylated Flavones and Their Biological Role in Metabolic Syndrome and Hyperlipidemia by Malkanthi Evans, Prachi Sharma and Najla Guthrie
Bioavailability of Citrus Polymethoxylated Flavones and Their Biological Role in Metabolic Syndrome and Hyperlipidemia by Malkanthi Evans, Prachi Sharma and Najla Guthrie
Chapter 15 Role of Aldehyde Oxidase and Xanthine Oxidase in the Metabolism of Purine-Related Drugs by Mohammad-Reza Rashidi and Roghiyeh Pashaei-Asl
Role of Aldehyde Oxidase and Xanthine Oxidase in the Metabolism of Purine-Related Drugs by Mohammad-Reza Rashidi and Roghiyeh Pashaei-Asl
Chapter 16 Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Anti-Neoplastic Agents by Daniel Lexcen, Ahmed Salem, Walid M. El-Khatib, Virginia Haynes and Ayman Noreddin
Pharmacokinetic/Pharmacodynamic (PK/PD) Modeling of Anti-Neoplastic Agents by Daniel Lexcen, Ahmed Salem, Walid M. El-Khatib, Virginia Haynes and Ayman Noreddin
Chapter 17 Pharmacokinetic (PK) and Pharmacodynamic Profiles of Artemisinin Derivatives Influence Drug Neurotoxicity in Animals by Qigui Li and Mark Hickman
Pharmacokinetic (PK) and Pharmacodynamic Profiles of Artemisinin Derivatives Influence Drug Neurotoxicity in Animals by Qigui Li and Mark Hickman
Chapter 18 One Step Closer to the Target: Intracellular Pharmacokinetics of Gemcitabine by Matthew Links and Peter Galettis
One Step Closer to the Target: Intracellular Pharmacokinetics of Gemcitabine by Matthew Links and Peter Galettis
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