Saffron-based crocin prevents liver cancer: Preclinical studies and beyond

Biomolecule of the golden spice is good for your liver

Date: January 4, 2016

Source: Bentham Science Publishers

Summary:

Liver cancer remains among the leading causes of cancer-related death worldwide. Now new research unravels mechanisms by which saffron-based 'crocin' protects against liver cancer.

Liver cancer remains among the leading causes of cancer-related death worldwide. New study lead by UAE University Prof. Amr Amin unravels mechanisms by which saffron-based 'crocin' protects against liver cancer.

The study entitled 'Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In Vivo, In Vitro and Network Analyses' is funded by Al-Jalila Foundation & Terry Fox Foundation and is published in Recent Patents on Anticancer Drug Discovery.

Using murine model, human liver cancer cells, gene expression profiling and computer-assisted modeling analyses, Amin's study identifies NF-kB as a regulatory hub and a candidate therapeutic drug target for liver cancer.

Story Source:

The above post is reprinted from materials provided by Bentham Science Publishers. Note: Materials may be edited for content and length.

Journal Reference:

Amr Amin, Alaaeldin A. Hamza, Sayel Daoud, Kamal Khazanehdari, Ala`a Al Hrout, Baig Ala`a, Amphun Chaiboonchoe, Thomas E. Adrian, Kourosh Zaki. Saffron-Based Crocin Prevents Early Lesions of Liver Cancer: In Vivo, In Vitro and Network Analyses. Recent Patents on Anti-Cancer Drug Discovery, 2015; 10 (999): 1 DOI:10.2174/1574892810666151102110248

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Bentham Science Publishers. "Saffron-based crocin prevents liver cancer: Preclinical studies and beyond: Biomolecule of the golden spice is good for your liver." ScienceDaily. ScienceDaily, 4 January 2016. <www.sciencedaily.com/releases/2016/01/160104080548.htm>.